They are ready to start serious talks with United boss Alex Ferguson hoping to seal a £22million move before the weekend’s Premier League opener.
United and Italian giants Juventus have yet to improve offers of £15m.
But Van Persie, 29, was jeered by his own fans in Sunday’s win over Cologne in Germany and is now desperate for a move to be completed.
Arsenal were demanding £25m for the Dutch striker, who has just one year left on his contract.
But the club will now settle for less — rather than have a player on their books who does not want to be there and could become a hate figure for the fans.
RVP scored 37 goals in all competitions last term, 30 of them in the Premier League.